[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2006]
From the U.S. Government Printing Office via GPO Access
TITLE 21--FOOD AND DRUGS
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN
PART 184_DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS
SAFE--Table of Contents
Subpart B_Listing of Specific Substances Affirmed as GRAS
Sec. 184.1545 Nitrous oxide.
(a) Nitrous oxide (empirical formula N2O, CAS Reg. No.
10024-97-2) is also known as dinitrogen monoxide or laughing gas. It is
a colorless gas, about 50 percent heavier than air, with a slightly
sweet smell. It does not burn but will support combustion. Nitrous oxide
is manufactured by the thermal decomposition of ammonium nitrate. Higher
oxides of nitrogen are removed by passing the dry gas through a series
of scrubbing towers.
(b) The Food and Drug Administration is developing food-grade
specifications for nitrous oxide in cooperation with the National
Academy of Sciences. In the interim, the ingredient
must be of a purity suitable for its intended use.
(c) In accordance with Sec. 184.1(b)(1), the ingredient is used in
food with no limitations other than current good manufacturing practice.
The affirmation of this ingredient as generally recognized as safe
(GRAS) as a direct human food ingredient is based upon the following
current good manufacturing practice conditions of use:
(1) The ingredient is used as a propellant, aerating agent, and gas
as defined in Sec. 170.3(o)(25) of this chapter.
(2) The ingredient is used in dairy product analogs as defined in
Sec. 170.3(n)(10) of this chapter at levels not to exceed current good
(d) Prior sanctions for this ingredient different from the uses
established in this section do not exist or have been waived.
[48 FR 57270, Dec. 29, 1983]
Additives that reference this regulation: