GrokFood Home
Loading

184.1372 Insoluble glucose isomerase enzyme preparations.

Home > Regulations > Direct food substances affirmed as generally recognized as safe > 184.1372 Insoluble glucose isomerase enzyme preparations.



[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2006]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR184.1372]

[Page 530]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 184_DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS 
SAFE--Table of Contents
 
        Subpart B_Listing of Specific Substances Affirmed as GRAS
 
Sec.  184.1372  Insoluble glucose isomerase enzyme preparations.

    (a) Insoluble glucose isomerase enzyme preparations are used in the 
production of high fructose corn syrup described in Sec.  184.1866. They 
are derived from recognized species of precisely classified 
nonpathogenic and nontoxicogenic microorganisms, including Streptomyces 
rubiginosus, Actinoplanes missouriensis, Streptomyces olivaceus, 
Streptomyces olivochromogenes, and Bacillus coagulans, that have been 
grown in a pure culture fermentation that produces no antibiotics. They 
are fixed (rendered insoluble) for batch production with GRAS 
ingredients or may be fixed for further immobilization with either GRAS 
ingredients or materials approved under Sec.  173.357 of this chapter.
    (b) The ingredient meets the general and additional requirements for 
enzyme preparations in the Food Chemicals Codex, 3d Ed. (1981), p. 107, 
which is incorporated by reference. Copies are available from the 
National Academy Press, 2101 Constitution Ave. NW., Washington, DC 
20418, or available for inspection at the National Archives and Records 
Administration (NARA). For information on the availability of this 
material at NARA, call 202-741-6030, or go to: http://www.archives.gov/
federal--register/code--of--federal--regulations/ibr--locations.html.
    (c) In accordance with Sec.  184.1(b)(1), the ingredient is used in 
food with no limitation other than current good manufacturing practice. 
The affirmation of this ingredient as generally recognized as safe 
(GRAS) as a direct human food ingredient is based upon the following 
current good manufacturing practice conditions of use:
    (1) The ingredient is used as an enzyme, as defined in Sec.  
170.3(o)(9) of this chapter, to convert glucose to fructose.
    (2) The ingredient is used in high fructose corn syrup, at levels 
not to exceed current good manufacturing practice.

[48 FR 5720, Feb. 8, 1983, as amended at 61 FR 43450, Aug. 23, 1996]





Additives that reference this regulation:


Source: U.S. Code of Federal Regulations - CFR Title 21, Part 184, Section 1372


Home | About | Search